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Prevention

From the rapid pace of pathogenesis to questions about vaccine boosters

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Why did the ACIP decide on a Category B recommendation for the MenB vaccines?

Why did the ACIP decide on a Category B recommendation for the MenB vaccines?

The Advisory Committee on Immunization Practices (ACIP) develops written recommendations for the routine administration of vaccines, in addition to schedules regarding the appropriate timing, dosage, and contraindications. Key factors – the balance between benefits and harm, the evidence type or quality, values and preferences, and health economic analyses – are used to refine the recommendation and to determine what category of recommendation is made, either Category A or Category B. Read more to discover why ACIP decided on a Category B recommendation for the MenB vaccines.

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What are the adverse effects of MenB vaccines?

What are the adverse effects of MenB vaccines?

There are two currently FDA-licensed MenB vaccines available in the United States. There are specific indications for the vaccine based on Category A (high-risk patients and situations) and Category B (healthy adolescents) as outlined by the Advisory Committee on Immunization Practices.
It is important to familiarize yourself with the vaccine that is used in your practice. Your personal and professional experience with the vaccine as the provider is important to be able to share with your patients, including the side effects associated with that particular vaccine.

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Can immunologic memory be outpaced by meningococcal disease pathogenesis?

Can immunologic memory be outpaced by meningococcal disease pathogenesis?

The pace of pathogenesis for Neisseria meningitidis infection is very rapid. In a matter of hours bacteria can attach to epithelial cells of the nasopharynx and then gain entry to the blood and lymphatics. From there the bacteria seed multiple sites such as skin and vital organs. The result is meningococcemia and, in some cases, meningococcal meningitis. The consequences are dire, with loss of limb and life.

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